Sunday, May 24, 2020
Cognitive Observation - 1488 Words
Method Media Used: Narrative, Pen and paper Time: Started 1.00pm Finished 1.10pm Number of Children Present: 4 Number of Adults Present: 2(including myself) Ages of children observed: 2:6 years 2:8 years 3 years 6.5 years Aim Rationale of observation: My aim while carrying out this observation was to observe a group of children, specifically the 2nd youngest child, aged 2yrs 8 months and his cognitive response to an activity involving numeracy. The type of cognitive skill I was looking for is what cognitive developmental stage children need to be at to be able to conserve and my colleague used Piagetââ¬â¢s Conservation Test involving Numbers to determine this. Background Information I am usingâ⬠¦show more contentâ⬠¦At this stage of development a child is more capable cognitively to conserve. Piaget considered the concrete stage a major turning point in the childs cognitive development because it marks the beginning of logical or operational thought. The child is now mature enough, cognitively, to use logical thought or operations (i.e. rules) but can only apply logic to physical objects (hence concrete operational). Children become less egocentric and better at conservation tasks. This means that the child understands that although the appearance of something changes, the thing itself does not. For example, if you take two pieces of string that are the same length and scrunch one up, a child will reply that the scrunched one is shorter, if conservation hasnt yet been reached. The other two children, aged 2.6 years and 3 years were still also in the Pre Operational Stage of development and so neither were at the cognitive development stage to enable them to conserve. Personal Learning: I found after carrying out this observation that children respond very well on a one to one basis, i.e. when the teacher was asking each individual child the questions relating to the Conservation test they all responded well and enjoyed the activity. I feel they felt they really belonged, therefore I was able to piece together the Aistear theme of Identity and BelongingShow MoreRelatedChild Observation : Cognitive And Language Development1711 Words à |à 7 Pages Child observation: #1 Cognitive and Language development Introduction: Name of the child: CJ Age: 2yrs and 10months (34 months) Date of observation: 6/19/2016 Time: 2.40pm to 4.40pm Context: Observation took place in their home. The living room dimension is approximately 16 x 20 feet, giving enough room for movement. On entering the living room, on the east corner is a 50-inch television and to the west is the dining set. This room is furnished with tan leather couches, center table and red rugRead MoreMeta Cognitive Observation1736 Words à |à 7 PagesPhilippines University Puerto Princesa Campus Puerto Princesa City EDUC 102: FACILITATING LEARNING ââ¬Å"Meta-Cognitive Observationâ⬠Submitted to: Mrs. Marites Espanueva-Lomocso Submitted by: Nerissa Mae F. Dadores Andrea Josefa D. Perez (BSED II) META-COGNITIVE OBSERVATION Introduction Metacognition refers to oneââ¬â¢s knowledge concerning ones own cognitive processes or anything related to them, e.g., the learning-relevant properties of information or data. ââ¬âJ. H. FlavellRead MoreChild Development : Play And Play885 Words à |à 4 Pagesaware of child-initiated play, parallel play and cooperative play but I did not consider observing as part of play. As a teacher, it is important for me to conduct observations to help me understand what stage a child is in during play, so I can help them bridge the childââ¬â¢s play to the next stage, if necessary. According to my Observations Taylor is in the observational play stage which can lead to other play styles such as solitary, onlooker, parallel, associative play and cooperative play accordingRead MoreMy Observation On Early Childhood Essay899 Words à |à 4 Pages Early childhood I choose to complete my observation on a three year old boy. His name is Brayden and he was born 01/12/12. He is on the younger side of this observation. The observation was completed at his home and in his yard. Some of the objects we used where a ball, cups, a bowl, water, MM candies, crayons, coloring books and play-doh. Being that Brayden is at a very active age, I started with the calmer task first. Therefore, I observed his socio-emotional development first. Brayden goesRead MoreObservation of the Early Childhood Essay1574 Words à |à 7 PagesObservation of the Early Childhood An observation was held in the childrens wing of Tarrant County Junior College. A variety of children between the ages of two to six were observed in activities ranging from physical and motor to social and cognitive development. Specifically I mean that whether it was leadership skills or lack of, running, climbing and jumping, drawing and writing, or anything that could fall between, it has been seen, done and accounted for in the following observationRead MoreMy Observation At Oakwood Methodist Preschool1693 Words à |à 7 PagesI conducted my observation at Oakwood Methodist Preschool on May 9, 2016 at 9:30 in the morning and 3:00 in the afternoon. The child I observed was a 16-month old female that I did have previously relations too. I use to work at Oakwood Methodist as an Extended Care Teacher. I use to care for Baby M in the infant room. During the observation there were two teachers, and 7 infants. The room that the observation took place in had many toys such as: balls, bouncers, walkers, rattles, and soft plushRead MoreThe Purpose Of This Essay Is To Evaluate The Use Of Observation1485 Words à |à 6 Pages The purpose of this essay is to evaluate the use of observation as a method of study within psychology. In order to undertake this evaluation the essay will initially discuss two traditional methods of investigation which are experimentation and observation. Furthermore, it will highlight differences between the two methods. In the second part of the essay, a deeper examination of the observational method itself will be undertaken. Here, examples of research in which the use of the observationalRead MoreEssay on Child Development Observation1013 Words à |à 5 PagesIn this assignment I am going to describe a child observation that I have done in a nursery for twenty minutes in a play setting. I will explain the strengths and weaknesses of naturalistic observation through the key developmental milestones based in Mary Sheridan (2005) check-list and provide a theoretical explanation to support the naturalistic observation. First of all I would like to explain why the child observation is important for social workers. It is important because it focus on theRead MoreA Reflection On Learning Theories And Assessment Strategies1616 Words à |à 7 Pages1987 cited by Walsh 2014). Hallgato et al (2013) define learning a skill is a process that is dependent on motor, cognitive and social skills. Following this ideas, the developed of this skill occurred in three distinct moments. Initially, it was developed by learning by observation, and later by repetition through problem-based learning around authentic problems. Learning by observation is supported by Banduraââ¬â¢s (1977) Social Learning Theory when one person learns by observing others doing it. ThisRead MoreChild Observation and Assessment Essay1956 Words à |à 8 Pagesoften the first child to arrive in the morning and the last to leave in the afternoon. I will focus on the social and emotional development of this child who, from now onwards, will be referred to as C. I carried out two types of observation: these being narrative observation and time sampling. I chose to do both because the strengths of each help to support the weaknesses of the other. The main weaknesses of time sampling are that it causes the observer to miss potentially important behaviours that
Wednesday, May 13, 2020
Little Women and Treasure Island Fatherhood - 2395 Words
Compare and contrast the depiction of fatherhoods in Little Women and Treasure Island. When discussing fatherhood in relation to both novels, we see that in both, the father is either primarily absent or irrelevant to the plot. The element of fatherhood comes from the characters designed to replace or substitute the absent or lost fathers. Treasure Island finds two figures available for Jim to form a paternal relationship, and the moral juxtaposition they present has as much to do with Jim growing into a moral man, as it does him choosing a path to survival. In Little Women fatherhood is represented by many different views of masculinity including Joââ¬â¢s attempt to fill her absent fatherââ¬â¢s shoes. The differences and similarities betweenâ⬠¦show more contentâ⬠¦Alcottââ¬â¢s decision to produce the sequel to Little Women greatly establishes the role fatherhood plays in her story, whilst Mr March is away, Jo is fulfilling her own prophecy of being ââ¬Å"the man of the familyâ⬠(Alcott, 1998 p.9) and upon his return is free to live her life as a à ¢â¬Ëlittle womanââ¬â¢, the significance of Bethââ¬â¢s death means Joââ¬â¢s desire to be a man is also over, and she strives to imitate her departed sister by neglecting the proactive and masculine personality she assumed in order to cope with being head of a household. In contrast to Alcottââ¬â¢s desire to be successful financially, Stevensonââ¬â¢s own efforts concerning Treasure Island were of a more innovative intent, to create a novel which not only featured a romantic story but served merely to entertain and inspire without an element of educating. Stevenson aspires to a more unconventional style of appealing to young boys, without moral preaching or the inclusion of religious implication; which Alcott endeavours to do with her inclusion of Bunyanââ¬â¢s Pilgrims Progress and her references to God, the most fatherly figure of all. ââ¬Å"If you learn to feel the strength and tenderness of your Heavenly Father as you do that of your earthly one. The more you love and trust Him, the nearer you will feel to Himâ⬠(Alcott, 1998 p.80) The fatherly characters are produced by two authors who had interesting relationships with their own fathers and who subsequently introduce their own opinions to the
Wednesday, May 6, 2020
Ways to get kicked out of your House Free Essays
The Reserve Bank of India had prompted the rupeeââ¬â¢s largest single-day rally since January 998 on 30th august by saying it would provide dollars directly to state oil companies to pay for imports, but the recovery proved short-lived. Economists have long argued that India needs to implement structural economic reforms to bring about meaningful progress. Last year, parliament lifted restrictions on foreign direct investment after much debate As a Citizen: As a citizen of India what I feel is middle class may not have lost faith yet in the economy. We will write a custom essay sample on Ways to get kicked out of your House or any similar topic only for you Order Now On the macro level there might be changes but as a common man or at the Cicero level I donââ¬â¢t see any great change except for the hike in prices. Due to the falling rupee the ââ¬Å"Marlââ¬â¢sâ⬠seem to have great opportunity to reap benefits from the Indian markets. Even the exporters will be benefited due to the fall in rupee. I definitely feel that this falling and depreciating economy is due to the coming elections. Even the financial conditions are easing are the interest rates are coming down. By : Fleshes shanghai 5 ways to get kicked out of your House By Afghanistanââ¬â¢s . Spoil your sisterââ¬â¢s wedding by insulting and throwing shoes and splitting on the guests. 5. Start roaming naked in your house. Economic situation. â⬠And what I feel is that it will be facing it for few more months. The Indian rupee has lost roughly 12% of its value during the past month. The major reason behind this can be because the country in importing more goods than it is. Micro level I donââ¬â¢t see any great change except for the hike in prices. Due to the By : Peevish shanghai How to cite Ways to get kicked out of your House, Papers
Monday, May 4, 2020
Confidentiality in Counselling free essay sample
Confidentiality in counselling means, to me, providing a secure, trusting relationship with a client who knows that, within certain limits, he or she can speak to you about anything at all in the knowledge that whatever has been said will go no further. It is an intrinsic and imperative part of the trust that is required to develop a good working relationship between a counsellor and their client. My client will know that, excepting those limits noted below, I will hold safe everything they share with me; their thoughts, their worries, their deepest secrets, their life story and they will leave our counselling sessions with the surety that they have a safe haven within which to explore their issues or problems. Similarly, if I speak to a friend, relative, or work colleague ââ¬Ëin confidenceââ¬â¢ I expect that what I have said will go no further than between ourselves unless I have told the listener otherwise and, by the same token, what they choose to tell me confidentially will not be shared by me with anyone else. If any acquaintance of mine, in any capacity, chose to talk to me about issues that may appear to be of a confidential nature, then I would implicitly consider that communication to be confidential unless that person advised me otherwise. In a work situation or in any other role where I may have access to confidential information, e. g. pupils, personnel, various group members, governing body discussions; I need to be aware of the confidential aspects that are a part of that information and ensure that I do not ââ¬Ëshareââ¬â¢ with any other person or agency that does not have access to the same details. When I am given confidential information the person or organisation giving it to me needs to feel sure that it will be kept as confidential and not imparted to a third party. ââ¬Å"Confidentiality is fundamental to the trust and integrity of the counselling relationship. It creates a safe space for the client to explore difficult and challenging issues and clearly signals that the client has control over any subsequent disclosures of that information or insights derived from it. â⬠(Bond P152 Para1 Lines 7-10) The following is an extract from the current BACP Ethical Framework: ââ¬Å"Fidelity: honouring the trust placed in the practitioner Being trustworthy is regarded as fundamental to understanding and resolving ethical issues. Practitioners who adopt this principle: act in accordance with the trust placed in them; regard confidentiality as an obligation arising from the clientââ¬â¢s trust; restrict any disclosure of confidential information about clients to furthering the purposes for which it was originally disclosed. â⬠There are, however, situations that may arise which would create exceptions to the basic rule of confidentiality in counselling. Confidentiality becomes the professional management of personally sensitive information disclosed in confidence. (Bond P152 Para 1 Line 1). The very nature of counselling means that a client may make disclosures which would lead me to consider breaking confidentiality and passing details of the disclosure to supervision. ââ¬Å"In actual practice all the national professional organisations for counsellors stress the importance of confidentiality but do not suggest that it should be absolute. To make it absolute would prohibit disclosures made in order to prevent serious harm to clients themselves or to others and would frustrate the requirements to receive counselling supervision. (Bond P153 Para 2 Lines 1-5) In such cases I would feel ethically and/or legally bound to report such a disclosure keeping the client informed of the process. The limits of confidentiality will have been explained to my client during my initial presentation of the contract between us, so that he or she would already be aware that what they tell me may be discussed with my supervisor, although their name will not be used. The following guidelines taken from the current BACP Ethical Framework note the need for such an action to be: i)where there is risk of harm to yourself or others; i)under the Prevention of Terrorism Act (Northern Ireland); iii)if the counsellor is subpoenaed or summoned as a witness in a Court of Law. ââ¬Å"Some threats to the public interest are considered sufficient to require a statutory obligation to disclose. These include matters concerning the prevention and detection of terrorism concerning Northern Ireland (Prevention of Terrorism (Temporary Provision) Act 1989), and drug trafficking (Drug Trafficking Offences Act 1986). Not to make a disclosure is an offence. Notifying people that you have made a disclosure about them constitutes a separate offence. â⬠(Bond P159 Para 4 Lines 1-8) The decision to take such action is not likely to be straightforward or obvious and I would have to be as sure as I could be that I was making the correct choice for all involved. Breaking confidence to protect the well-being of either my client or another person, perhaps myself, because I considered the possibility of that danger to be real, is a difficult and crucial decision to make and I must feel that there is significant danger of harm. One of the great weaknesses of the current ethical and legal arrangements with regard to confidentiality is that the complexity must create a degree of uncertainty for counsellor and client. â⬠¦.. The law has taken the view that confidentiality cannot be justified as an absolute principle. â⬠¦Ã¢â¬ ¦Ã¢â¬ (Bond P166 Para 2 Lines 1-3 11-12) Whenever possible my first course of action would be to discuss my decision with my client and encourage him or her to inform the authorities themselves. If they were unable or unwilling to do this then my next step would be to take their story to supervision and if I was still convinced that, in this case, confidentiality needed to be broken, then I would take the necessary steps to report the situation. The law suggests I exercise ââ¬Å"reasonable careâ⬠in my judgement and I would need to keep detailed records of my discussion with my client regarding this course of action so that I had evidence should a complaint be made against me. Another possible situation in a counselling session which could require that confidentiality be broken is where a disclosure has been made regarding child abuse or incest. It is a contracted condition of some agencies that their counsellors take to supervision any such child protection issues and again this will have been explained to my client when discussing our contract. ââ¬Å"The Childrenââ¬â¢s Act 1989 is of a much more limited jurisdiction than is commonly understood. The statutory obligation to report and investigate incidents of child abuse is largely confined to social services. (Bond P159 Para 5 Lines 1-4). The limits of confidentiality need to be made explicitly clear during the initial meeting with my client so that if a breach should become necessary he or she will already be aware of the possibility of such an event and hopefully, therefore, be less affected by it than may otherwise have been the case. There could be negative consequences as a result of my having made the decision to breach the confidentiality of out client/counsellor relationship. They may feel let down and (even having given their permission for me to pass on their story) betrayed. However, if I have handled the situation correctly, gained my clientââ¬â¢s trust with an assurance that whatever I do is still with the intention of helping them, that I am not passing judgement and will not be abandoning them, then, hopefully, they may be able to see that passing on their story is intended to be a positive step forward. I would try to show them that the positivity would be in meeting the need for them to take on the responsibility of their actions in order to gain autonomy in their own life. The counsellorââ¬â¢s commitment to confidentiality marks a boundary that supports ethical principles of respect for client autonomy and fidelity and places the client in control of decisions about the clientââ¬â¢s best interests and the avoidance of harm outside the counselling relationship. â⬠(Bond P152 Para 1 Lines l1-14) Although I could not feel uninvolved in a serious disclosure I would have to keep myself detached enough that I would be seeing the path I needed to follow clearly, without allowing my own emotions to cloud my judgement. The weight of this burden of responsibility may lay very heavily, however, I need to be clear headed in my duty to disclose information which I know I am legally bound to do. In a more serious situation, even though the correct procedures have been followed and my client has been made aware of my intention to break confidentiality, it is possible that they may decide to make a complaint or even to instigate legal proceedings against me. Under any circumstances breaching confidentiality is a very serious step to take in the relationship between counsellor and client and should never be taken lightly or without the ââ¬Å"reasonable careâ⬠that is the counsellorââ¬â¢s responsibility. ââ¬Å"A breach of confidence is defensible where: (a) The client has consented to disclosure. Obtaining the clientââ¬â¢s consent is often the best way of resolving legal and ethical disclosures over confidentiality (Cohen, 1992);â⬠(Bond P158 Para 3 Lines 4-7) Notwithstanding all of the above there are then my own limits of ability, understanding and knowledge to consider within a counsellor/client relationship. I would be doing any client a disservice if I were to continue to counsel them when I was aware that the interaction had reached a stage where I was unqualified, unable or unwilling to deal with it well and/or appropriately. It would be unethical for me to continue without consulting the client and offering them alternative options which would necessitate my breaching confidentiality. I would assure them that this breach would be limited to passing on their story to my supervisor, with their permission, and that I could continue to see them whilst another, better suited or more qualified person was being found for them. It is of paramount importance that I am aware of the various alternatives of help that are available for my client so that I can signpost quickly and positively, thereby making the transition as ââ¬Ëpainlessââ¬â¢ as possible. Confidentiality forms the basis of counselling. It is what bonds client and counsellor on their journey together and helps them to work openly and honestly with trust and respect for each other. If the client has a firm belief that confidentiality is at the base of the consultation process then he or she can feel empowered to explore any issue they need to that will enable them to go forward into a more autonomous future. Bibliography Tim Bond 2000 Standards and Ethics for Counselling in Action Second Edition Sage Publications
Saturday, March 28, 2020
American Bungalow Essays - Bungalow, The Aladdin Company
American Bungalow Essays - Bungalow, The Aladdin Company American Bungalow The article Manufacturing and Marketing the American Bungalow by Scott Erbes discusses the effects that The Aladdin Company had on the American Bungalow. The Aladdin Company was a main manufacturer of these mail order homes. By intense marketing and propaganda the Aladdin Company, along with several others, was able to promote and sell these precut homes by mail. The Aladdin Company was founded in 1906 in Bay City, Michigan by William and Otto Sovereign. William and Otto started their firm having had no architectural experience at all. They were inspired by a friend who was in the business of selling precut boats by mail so they decided to venture into selling precut homes by mail. In order for William and Otto to get their company started and up to the level that they wanted, it became necessary to use mass-marketing as a ploy to draw people into the idea of homes through the mail. Their way of enticing people to buy these homes was through their catalogue. They portrayed the homes by mail, bungalows, as an escape from lifes worries: A place where one could commune with nature. By taking the promotional aspect to such a high level the bungalow became very prominent in the America in the early 1900s. By 1917, William and Otto were selling more than three thousand homes per year. They had homes spread all over the United States and included in that array of owners were several large- scale companies such as the Dupont Company. Their success continued for the next two decades and William and Otto were able to broaden their product line from not only the houses but also the furnishings in the houses. However, the companies momentum was nearly depleted during the Great Depression. Aladdins output dropped drastically during the Great Depression but in the decades following the Depression, it was able to regain some of their profit but they never reached the level that they were at before the Depression. Finally, in the 1980s the company had to shut down because of the lack of profit. The author, Scott Erbes, focuses heavily on the different types of the bungalow and on their origin. The word bungalow comes from the work Bangla, which is a hut-like dwelling from the region of Bengal, India. This origin design was greatly altered by the time it reached the United States. The interpretation of the Bangla into what Aladdins designers felt it needed to look like was drastically different. The design went from something portable to something that was permanent and used for seasonal outings. People used their bungalows as their vacation homes and eventually the bungalows became the year round residents for some of the lower middle class people. It becomes very obvious that a creation as largely accepted as this one, would attract a large amount of attention from the media. The bungalow received both good and bad reviews depending on the person. Some were crazy about the idea while others were very critical of the use of these dwellings for permanent use. They claimed that the structure had no architectural creativity at all and that they were boring. It is very intriguing that something as petty as a mail order home could be as popular as it was for the time period that it was. For William and Otto to think of this idea and to actually be able to make a profit off of it is very praiseworthy. They took a risk when they ventured into the business but it paid of when they were able to promote an ideas that spawned so many other companies to do the same thing. Also, to be able to overcome the overwhelming disapproval of some critics is admirable. Aladdins idea for the bungalow was very versatile and therefore it appealed to the middle class. The middle class would be able to buy a home like this and be able to change it around as they saw fit for what they needed. The way that the author compares the bungalow to the log cabin becomes very intriguing. He says that the bungalow is the modern day log cabin. The way that the author relates these two allows you
Saturday, March 7, 2020
The Stock Market Crash of 1929
The Stock Market Crash of 1929 Free Online Research Papers The stock market has been around and well-known for many years and has been dated back into colonial times. However, in 1929, the stock market unfortunately took a drastic turn for the worst. In just a matter of days, the market underwent a cascading decline, and took everything down with it. To many, the stock market may seem very complicated and esoteric. However, after some research some come to find its actually very simple, because someone else basically does the work for you. This ââ¬Ësomeone elseââ¬â¢ is a stock broker. In simpler terms, a stock broker is like an auctioneer. The job of an auctioneer is to pair a buyer with a seller, much like the job of a stock broker. They also determine adequate pricing of whatever it is being sold (Gerlach). In the stock market, shares of companies are what is being sold. If you buy a share of a stock, you own a part of that company. Generally, if the company did well, you would earn a profit, and if it didnt do so well, you could potentially lose money. Investors soon purchased stock on margin. Margin is the borrowing of stock for the purpose of getting more leverage. For every dollar invested, a margin user would borrow 9 dollars worth of stock. Because of this leverage, if a stock went up 1%, the investor would make 10%! If a stock drops too much, a margin holder could lose all of their money AND owe their broker money as well (Stock Market Crash). Investing money in the stock market was a very risky act. Some lucky investors end up acquiring huge profits and simultaneously become millionaires over night. However a lot of patience is necessary as not to panic and sell your share as soon as the prices drop in the slightest bit. Keeping calm through a downfall could ultimately be your saving grace in the end. Because more and more Americans were purchasing stocks, the value of the marked drastically increased (Ohio History Center). There was a peak in prices in September 1929, and after this, the priced dropped. Some brokers were on the brink of panic and quickly called in there loans, which would have been a wise decision. On the other hand, many brokers carried on, continuing to loan money, and looked at the decline as just a bad day in the market. On Wednesday October, 23rd, the Dow Jones had descended 24 points in a mere half hour, causing a slight panic across the nation. The next day, Thursday the 24th, all brokers called in their loans causing all prices on the market to face a gargantuan downfall. Many at this point figured the stock market just need a few days to bounce back. To keep a lid on the hysteria, brokers began to merge their funds to buy enough stocks to even out the market. This briefly balanced the priced. However, by the following Monday, prices had fallen again. Tuesday October 29th, 1929, ââ¬ËBlack Tuesday,ââ¬â¢ was the day all hell had broken loose. This was the very day of the stock market crash. Because of the rapidly declining prices, the once reliable ticker tape had trouble keeping up and ended up causing mass confusion and chaos. On account of the dwindling prices, many people vacated the market and withdrew all their funds while their debts were still meager. With everyone pulling out at once, mass mayhem had occurred and the market had crashed. After the crash, the suicide rate skyrocketed. Many people leapt to their demise out of tall buildings because being dead was easier than facing financial debt. The most abundant time of suicides came in 1930, the year following the crash. In 1925 the number of suicides in New York was 14.4 per 100,000 of the population. In 1934, that number had escalated to 17.0 per 100,000 of the population (Galbraith). Also, the stock brokers who decided suicide was not the answer, lost their jobs. American across the nation were in debt. However, it was the Americans who has invested all they had who were hit the hardest and has lost everything as a result of the crash. Eventually the crash of the stock market has negatively effected everyone. Research Papers on The Stock Market Crash of 1929Analysis of Ebay Expanding into AsiaTwilight of the UAWQuebec and CanadaThe Effects of Illegal ImmigrationDefinition of Export QuotasMarketing of Lifeboy Soap A Unilever ProductAppeasement Policy Towards the Outbreak of World War 2Open Architechture a white paperHip-Hop is ArtBionic Assembly System: A New Concept of Self
Wednesday, February 19, 2020
GENE THERAPY (VIRAL AND NON-VIRAL VECTORS) Essay
GENE THERAPY (VIRAL AND NON-VIRAL VECTORS) - Essay Example HVS (Harpes Simplex Virus Vector) happens to be the most complex as well as the largest among all viruses under development for gene therapy with one of its features of importance being that it has a capacity that is able to carry he fragments for foreign DNA (Mohammed, Al-Dosari1, & Xiang 2009). Hybrid vectors- in demand for better vectors, most researchers are trying to combine significant features of distinct viruses in hybrid vectors. Among the fascinating hybrids brings together the site specific integration machine for wild type AAV together with the nuclear targeting as well as efficient internalization properties of adenovirus (Clare, Anja, & Mark 2003). There seems to be a bright future for vectors given that vectors development within the past several years has encouraging results. Less immunogenic vectors have been deleted through creation of new gene production systems that are efficient. The haematopietic cellsââ¬â¢ ex vivo transduction has been improved in its efficiency. The in vivo trans-gene expression has been improved in its efficiency and specificity by means of tissue specific optimization as well as inducible promoters. There has been expansion of vector tropisms repertoire as well as pre-existing immune responses evasion by developing alternative viral serotypes (Clare, Anja, & Mark 2003). Several applications of gene therapy look promising in clinical early phase trial for instance haemophilia B treatment by use of rAAV, vascular and coronary artery disease treatment by use of viral vectors and certain kinds of cancer treatment by use of ââ¬Å"conditionally replicating ecolytic virusesâ⬠(Kenneth & Teni 2003). Viral-vectors- Typically, viral vectors do consist of viral particles that have nucleic acid with a capseid protein covering it at least and mostly further by the structure of an envelope. In general, one or a number
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